Medicine "Famotidine". Instructions for use
The means "Famotidine" - a drug that has anti-ulcer effects. Partially absorbed the drug. The highest content in the body reaches the drug for an hour to three. The drug Famotidine, whose mechanism of action is based on a blocking effect on histamine H2 receptors, suppresses the production of (basal and stimulated) hydrochloric acid, as well as pepsin activity. The duration of the effect of the drug lasts for ten to twelve hours. When injected into a vein, the maximum effect is noted after thirty minutes.
Medicine "Famotidine". Instructions for use. Indications
A remedy is prescribed for the treatment and prevention of peptic ulcer of a different nature of occurrence, including those caused by the intake of NSAIDs (nonsteroidal anti-inflammatory drugs), stressful situations, the postoperative period.Other indications include erosive gastroduodenitis, systemic mastocytosis, reflux esophagitis, bleeding (relapse prevention), polyendocrine adenomatosis. The drug Famotidine recommends that the instructions for use should be taken for functional dyspepsia associated with increased secretion in the stomach.
The drug is intended for intravenous and oral use. When exacerbation of ulcerative pathology is prescribed twice a day, 20 mg or 40 mg at bedtime. If necessary, according to the recommendation of a specialist, the daily dosage can be increased to 80-160 mg. The duration of treatment is usually from four to eight weeks. For the prevention of exacerbations take 20 mg at night. For intravenous (jet) administration, the optimal dosage is 20 mg with an interval of 12 hours. Once allowed no more than 20 mg.
The tool "Famotidine" instructions for use does not recommend prescribing during pregnancy, hypersensitivity, in childhood. When treating a peptic ulcer it is necessary to exclude the presence of a tumor (malignant).Particular care must be taken in case of cirrhosis with hepatic encephalopathy.
On the background of drug treatment may decrease appetite, nausea, dry mouth, abdominal pain, vomiting. The drug provokes arthralgia, myalgia, jaundice, constipation, acute pancreatitis, hepatitis (hepatocellular, or cholestatic, or mixed). The tool "Famotidine" (instructions for use contains this information) can cause arrhythmia, bradycardia, lowering blood pressure, neutropenia, leukopenia, vasculitis, atrioventricular blockade.