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Aging is not a disease: How to be healthy at any age
Of course, it would be good to drink living water or eat rejuvenating apples, in case of emergency, take some pills and stay young forever.
How to maintain health
For thousands of years, the elixir of immortality was sought by shamans, priests and alchemists. Of course, it would be good to drink living water or eat rejuvenating apples, in case of emergency, take some pills and stay young forever.
Unfortunately, the elixir of youth has not yet been invented, but there are already medications to fight aging, and the day is not far when doctors will prescribe them to us.
Many people cannot even guess, but now there are about 200 names of geroprotectors, potentially capable of prolonging a person’s life.
In the instructions for these medicines, you will not read that they can be prescribed to slow down aging.How to explain it? Medicines are registered for the treatment of specific diseases, and old age, unfortunately, is not officially considered a disease.
Plus, due to the considerable life expectancy of a person, the tests for its extension can be very long. Therefore, these properties of drugs, as a rule, are only tested on laboratory animals and information about them cannot yet be used as a recommendation for self-treatment.
Aging, from a medical point of view, is not a disease. The generally accepted biomarker, by which one could understand whether this process is slowing down or not, also does not exist.
Therefore, the goal of research is to find drugs that can slow the development of age-related diseases: cardiovascular, neurological, oncological, and so on.
Derived from French lilac, or goat's rue (Galega drug, or goat's herb), the drug Metformin, in addition to the treatment of type 2 diabetes, is used to treat non-alcoholic fatty liver, and is currently being tested as a means to prevent various types of cancer.
According to some scientists, metformin causes approximately the same changes in the body as calorie restriction: it increases insulin sensitivity, lowers cholesterol, and improves physical condition.
American scientists analyzed the health and life expectancy of 70 thousand patients with diabetes who took Metformin. The risk of developing cancer was lower by 35–40% compared with those who did not take this drug, and they lived 15% longer.
Aging of the cardiovascular system begins with vascular atherosclerosis. Then high blood pressure may develop, which overloads the heart and causes it to wear out faster.
Metformin has been proven to delay aging of the heart and blood vessels, slowing the development of such senile diseases as chronic heart failure, atherosclerosis, atrial fibrillation, aortic aneurysm, peripheral arterial disease, vascular calcification.
Metformin has already been recognized by the American Drug Control Authority (an analogue of our Pharmaceutical Committee) geroprotector. And in the USA it is already prescribed as a medicine that removes aging.
Sildenafil has received worldwide fame thanks to a side effect. The drug is manufactured by Pfizer under the brand name "Viagra" and was developed as a medicine for coronary heart disease, but the results of clinical studies conducted in 1992 disappointed the developers of the drug.
However, its side effect, which was reported by many study participants, namely: a pronounced effect on the blood flow in the pelvic organs, prompted the idea of using this medication for the treatment of erectile dysfunction.
Later, other properties of sildenafil were found to decrease the pressure in the pulmonary artery, dilate blood vessels and restore their elasticity.
These properties allow you to prevent a number of age-related changes that cause diseases that are leading in the list of causes of death - heart attack, stroke, senile dementia, vascular atherosclerosis.
Rapamycin, discovered by a Brazilian researcher as a product of the metabolism of Streptomyces hygroscopicus bacteria from a soil sample from Easter Island, is mainly used as an immunosuppressant to prevent rejection of organs and tissues.
It is used as an antifungal antibiotic and after an organ transplant so that they do not reject. In the experiment, he increased the lifespan of yeast, nematode, fruit fly and old mice by 26%.
Moreover, in mice, this action was confirmed in eight different independent studies. Rapamycin blocks a certain protein and thus causes the same changes in the body as with a significant reduction in caloric intake. It is this diet that really helps to prolong life.
However, the drug has side effects, including: an increase in insulin resistance, which can cause diabetes. Metformin can be a solution to this problem and has already shown efficacy in some patients with diabetes.
If the findings of the researchers are confirmed by the results of larger-scale trials, a combination of metformin and rapamycin will be used to treat aging and age-related diseases.
Academician Skulachev, who is studying the aging process, proposed a tool called “Drops of Skulachev,” a powerful antioxidant that prevents the negative effects on the body of free radicals.
Today, Vizimitin eye drops are actively offered for sale, and the release of the drug from old age has been postponed for the time being, since all the necessary tests and studies have not been carried out. In 2016, it was reported that the cure for old age is already in pharmacies, but so far no data on its production and sale is available.
Melatonin was discovered in 1958. It is a hormone that is produced in our body at night, in the dark, and is a regulator of sleep and biorhythms. In the 70s of the last century, scientists found that melatonin, administered as a drug to rats and mice, prolongs their life.
As a means of preventing aging, melatonin is already prescribed in the United States. In Russia, it, as well as Metformin, is already used in the treatment of cancer. And the use of melatonin as a geroprotector that removes aging is a matter for the near future.
Simple and effective means
In addition to receiving special preparations, gerontologists strongly advise to pay attention to simple and effective means.
Reduces the incidence of age-related diseases (cardiovascular, metabolic and others), slows down aging at the cellular level.
Increases the maximum lifespan of mice by 7%.
Reduces all-cause mortality by 46%, and has a general healing effect on the body.
Reduces the mortality of experimental mice by 7%.
Extends the life of mice by 18%.
Nicotinamide riboside (aka NMN drug)
Increases the lifespan of mice by 15%.
Products to slow the aging body
Here is a list of the most useful products for maintaining health and slowing down cell aging.
All types of nuts are a source of antioxidants, vitamins and minerals, supplying the body with a mass of essential substances.
Natural antioxidants that help eliminate toxins and free radicals.
Reduce the level of lipoproteins in the blood, contribute to the healing of the cardiovascular system.
Source of essential fatty acids.
Supplier of protein - a building material for cells.
The fight against aging should be carried out daily. No magic pill of old age will help if you do not look after your health and try to keep all organs and systems in working order.
Before you buy any anti-aging products, do not forget to consult your doctor.